Acetaminophen + Diphenhydramine

Fixed-dose combination

This page lists brands whose active-ingredient set is exactly the combination below. It is identity information only — a fixed-dose combination is not the same product as its single ingredients, and the brand names are not interchangeable across markets.

Not medical advice. Check the pack and the exact composition before comparing products; ask a pharmacist if unsure.

Active ingredients

Acetaminophen acetaminophen
Diphenhydramine diphenhydramine

Brands with this exact combination

Brand	Composition & strength	Manufacturer
Acetaminophen, Diphenhydramine HClUS	50 mg/30 mL / 1,000 mg/30 mL / 500 mg / 25 mg / 325 mg / 12.5 mg	The Procter & Gamble Manufacturing Company
Acetaminophen and Diphenhydramine HydrochlorideUS	500 mg / 25 mg / 650 mg/20 mL / 25 mg/20 mL / 650 mg / 325 mg	Lil' Drug Store Products, Inc.
ACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDEUS	500 mg / 25 mg / 320 mg/10 mL / 12.5 mg/10 mL / 1,000 mg/30 mL / 50 mg/30 mL	Strive Pharmaceuticals Inc.
Pain Relief PM Extra StrengthUS	tablet ×13 Acetaminophen 500 mg + Diphenhydramine 25 mg	Allegiant Health
Pain Reliever PM Extra StrengthUS	tablet ×13 Acetaminophen 500 mg + Diphenhydramine 25 mg	L.N.K. International, Inc.
Pain Reliever PMUS	tablet ×12 Acetaminophen 500 mg + Diphenhydramine 25 mg	WALMART INC.
ACETAMINOPHEN PMUS	tablet ×10 Acetaminophen 500 mg + Diphenhydramine 25 mg	AAA Pharmaceutical, Inc.
Acetaminophen PM Extra StrengthUS	tablet ×9 Acetaminophen 500 mg + Diphenhydramine 25 mg	United Natural Foods, Inc. dba UNFI
Acetaminophen and Diphenhydramine HClUS	500 mg / 25 mg / 325 mg / 12.5 mg	Haleon US Holdings LLC
Paracetamol 120mg/5ml / Diphenhydramine 12.5mg/5ml oral solutionGB	120 mg/5 mL / 12.5 mg/5 mL / 500 mg / 25 mg / 7 mg/5 mL	McNeil Products Ltd
Tylenol PM Extra StrengthUS	tablet ×6 Acetaminophen 500 mg + Diphenhydramine 25 mg liquid Acetaminophen 1,000 mg/30 mL + Diphenhydramine 50 mg/30 mL	Kenvue Brands LLC
Acetaminophen, DiphenhydramineES US	500 mg / 25 mg	Pioneer Life Sciences, LLC
Diphenhydramine Hydrochloride and AcetaminophenUS	1,000 mg/30 mL / 50 mg/30 mL / 25 mg / 500 mg	The Procter & Gamble Manufacturing Company
Extra Strength Acetaminophen PMUS	tablet ×4 Acetaminophen 500 mg + Diphenhydramine 25 mg	BJWC (Berkley & Jensen / BJ's)
EXTRA STRENGTH PAIN RELIEVER PMUS	tablet ×3 Acetaminophen 500 mg + Diphenhydramine 25 mg	INGLES MARKETS, INC.
Vicks PainQuil PM PAIN RELIEVER plus NIGHTTIME SLEEP-AIDUS	liquid ×2 Acetaminophen 1,000 mg/30 mL + Diphenhydramine 50 mg/30 mL	The Procter & Gamble Manufacturing Company
Pain Reliever PM, Extra Strength, 24-7 Life by 7-ElevenUS	tablet ×2 Acetaminophen 500 mg + Diphenhydramine 25 mg	Lil' Drug Store Products, Inc.
Vicks ZzzQuil Night PainUS	liquid Acetaminophen 1,000 mg/30 mL + Diphenhydramine 50 mg/30 mL tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	The Procter & Gamble Manufacturing Company
meijer EXTRA STRENGTH Pain Relief PM CapletUS	tablet ×2 Acetaminophen 500 mg + Diphenhydramine 25 mg	Meijer, Inc.
good sense pain relief pm extra strengthUS	tablet ×2 Acetaminophen 500 mg + Diphenhydramine 25 mg	Bryant Ranch Prepack
Vicks ZzzQuil NIGHT PAIN NIGHTTIME SLEEP-AID PAIN RELIEVERUS	liquid ×2 Acetaminophen 1,000 mg/30 mL + Diphenhydramine 50 mg/30 mL	The Procter & Gamble Manufacturing Company
Diphenhydramine HCl, AcetaminophenUS	50 mg/30 mL / 1,000 mg/30 mL	The Procter & Gamble Manufacturing Company
PANADOL PMUS	tablet ×2 Acetaminophen 500 mg + Diphenhydramine 25 mg	Haleon US Holdings LLC
acetaminophen and diphenhydramineUS	500 mg / 12.5 mg / 25 mg	Medtech Products Inc.
Tylenol PM Extra Strength, CVP HEALTHUS	tablet ×2 Acetaminophen 500 mg + Diphenhydramine 25 mg	Lil' Drug Store Products, Inc.
CAREALL Pain Relief PM Extra StrengthUS	tablet ×2 Acetaminophen 500 mg + Diphenhydramine 25 mg	New World Imports, Inc
Dr. Simi Pain Reliever PMUS	tablet ×2 Acetaminophen 500 mg + Diphenhydramine 25 mg	Farmacias De Similares TX LLC
Acetaminophen and Diphenhydramine citrateUS	500 mg / 38 mg	InvaTech Pharma Solutions LLC
Dozol liquidGB	liquid ×2 Acetaminophen 120 mg/5 mL + Diphenhydramine 12.5 mg/5 mL	Manx Healthcare Ltd
paracetamol + difenhidraminaES	25 mg / 500 mg	Esteve Pharmaceuticals S.A.
RiteAid Nighttime Sleep AidUS	liquid Acetaminophen 1,000 mg/30 mL + Diphenhydramine 50 mg/30 mL	RITE AID CORPORATION
Robitussin Honey Severe Cough, Flu Plus Sore Throat NighttimeUS	liquid Acetaminophen 650 mg/20 mL + Diphenhydramine 25 mg/20 mL	Haleon US Holdings LLC
Chloraseptic Nighttime Sore Throat Hot ReliefUS	powder Acetaminophen 650 mg + Diphenhydramine 25 mg	Prestige Brands Holdings, Inc.
Dimetapp Multi-Symptom Cold and FluUS	liquid Acetaminophen 320 mg/10 mL + Diphenhydramine 12.5 mg/10 mL	Foundation Consumer Healthcare
NOTTS - Pain Relief PMUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	VIVUNT PHARMA LLC
Pain Relief Acetaminophen PMUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Rite Aid Corporation
Extra Strength Pain Relief PMUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	VALU MERCHANDISERS COMPANY
Extra Strength Nite-Time Pain ReliefUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	WALGREENS
430R WALGREENS Acetaminophen 500 mg,Diphenhydramine HCl 25 mg TabletUS	500 mg / 25 mg	WALGREENS
CVS Nighttime Sleep AidUS	liquid Acetaminophen 1,000 mg/30 mL + Diphenhydramine 50 mg/30 mL	CVS PHARMACY
equate pain relief pmUS	liquid Acetaminophen 1,000 mg/30 mL + Diphenhydramine 50 mg/30 mL	WALMART INC.
Pain Relief Acetaminophen PM Extra StrengthUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Rite Aid Corporation
Pain Reliever plus Sleep Aid NightTimeUS	liquid Acetaminophen 1,000 mg/30 mL + Diphenhydramine 50 mg/30 mL	Kroger Company
Unisom PM Pain Nighttime Sleep Aid and Pain RelieverUS	tablet Acetaminophen 325 mg + Diphenhydramine 50 mg	Chattem, Inc.
RIGHT REMEDIES EXTRA STRENGTH PM Pain ReliefUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Strive Pharmaceuticals Inc.
basic care acetaminophen pmUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Amazon.com Services LLC
Theraflu Severe Cold Relief Nighttime Soft ChewsUS	tablet Acetaminophen 325 mg + Diphenhydramine 12.5 mg	Haleon US Holdings LLC
Nighttime Pain Reliever plus Sleep AidUS	liquid Acetaminophen 1,000 mg/30 mL + Diphenhydramine 50 mg/30 mL	WALMART INC.
ValuMeds Pain Relief PM Pain Reliever and Nighttime Sleep Aid Acetaminophen, Extra StrengthUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Cabinet Health P.B.C.
Goodmeds Extra Strength Pain Relief PMUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Cabinet Health P.B.C.
Allergy and HeadacheUS	tablet Acetaminophen 325 mg + Diphenhydramine 25 mg	CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED
Vicks NyQuil HOT REMEDY Cold and FluUS	powder Acetaminophen 650 mg + Diphenhydramine 25 mg	Procter & Gamble Manufactura S de RL de CV
Percogesic Extra StrengthUS	capsule Acetaminophen 500 mg + Diphenhydramine 12.5 mg	Medtech Products Inc.
Allergy Plus Headache ReliefUS	tablet Acetaminophen 325 mg + Diphenhydramine 25 mg	WALMART INC.
Vicks PainQuil PM LIQUICAPS PAIN RELIEVER plus NIGHTTIME SLEEP-AIDUS	capsule Acetaminophen 500 mg + Diphenhydramine 25 mg	The Procter & Gamble Manufacturing Company
Robitussin Maximum Strength Severe Multi-Symptom Cough Cold Flu NighttimeUS	liquid Acetaminophen 650 mg/20 mL + Diphenhydramine 25 mg/20 mL	Haleon US Holdings LLC
Extra Strength NiteTime Pain ReliefUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	WALGREENS
Genexa Acetaminophen PM Extra StrengthUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Genexa Inc.
Percogesic Original StrengthUS	tablet Acetaminophen 325 mg + Diphenhydramine 12.5 mg	Medtech Products Inc.
Cystex PMUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Clarion Brands, LLC
RIGHT REMEDIES EXTRA STRENGTH Pain Relief PM CapletUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Strive Pharmaceuticals Inc.
Kroger EXTRA STRENGTH Acetaminophen PM CapletUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	The Kroger Co.
Sleep Aid Plus Pain ReliefUS	liquid Acetaminophen 1,000 mg/30 mL + Diphenhydramine 50 mg/30 mL	Walgreen Company
dg health pain relief pm extra strengthUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Dolgencorp Inc
GOODYS PMUS	powder Acetaminophen 500 mg + Diphenhydramine 38 mg	Medtech Products Inc.
GOOD REMEDIES Extra Strength Pain Relief PM CapletUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Strive Pharmaceuticals Inc.
Tylenol PMUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Savings Distributors LLC
CareOne Acetaminophen PMUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	American Sales Company
CounterAct PMUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Melaleuca, Inc.
Extra Strength Night Time Pain MedicineUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Geri-Care Pharmaceutical Corp
Lil Drug Store Tylenol PM Extra StrengthUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Lil' Drug Store Products, Inc.
Equate Severe Cold Cough and FluUS	powder Acetaminophen 650 mg + Diphenhydramine 25 mg	WALMART INC.
Extra Strength PM Pain MedicineUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Amerisource Bergen
CAREALL Non-Aspirin PM Extra StrengthUS	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	New World Imports, Inc
Medised For Children oral solutionGB	liquid Acetaminophen 120 mg/5 mL + Diphenhydramine 12.5 mg/5 mL	SSL International Plc
Panadol NightPain tabletsGB	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Haleon UK Trading Ltd
Tixyplus Active Relief for Colds + Flu oral suspensionGB	liquid Acetaminophen 120 mg/5 mL + Diphenhydramine 7 mg/5 mL	Novartis Consumer Health UK Ltd
CalCold Six Plus oral solutionGB	liquid Acetaminophen 120 mg/5 mL + Diphenhydramine 12.5 mg/5 mL	McNeil Products Ltd
Calpol Night oral solutionGB	liquid Acetaminophen 120 mg/5 mL + Diphenhydramine 12.5 mg/5 mL	McNeil Products Ltd
ANTIDOL NOCHEES	tablet Acetaminophen 25 mg + Diphenhydramine	Laboratorios Cinfa S.A.
DOLOMIDINA 500/25MGES	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Esteve Pharmaceuticals S.A.
NIGHTIXMX	tablet Acetaminophen + Diphenhydramine	LABORATORIOS DIBA, S.A.
MersynoNight Night Time Pain ReliefAU	unknown Acetaminophen + Diphenhydramine	—
diphenhydramine hydrochloride + acetaminophenAU	—	—
ACETAMINOPHEN WITH ANTIHISTAMINE NIGHTTIMECA	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	LABORATOIRES TRIANON INC.
CORICIDIN II NIGHT TIME COLD AND FLUCA	tablet Acetaminophen 325 mg + Diphenhydramine 25 mg	SCHERING-PLOUGH HEALTHCARE PRODUCTS CANADA, A DIVISION OF SCHERING CANADA INC.
EXTRA STRENGTH TYLENOL ALLERGY AND COUGHCA	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	MCNEIL CONSUMER HEALTHCARE DIVISION OF JOHNSON & JOHNSON INC
EXTRA STRENGTH TYLENOL PAIN AND HEAD COLD NIGHTCA	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	MCNEIL CONSUMER HEALTHCARE DIVISION OF JOHNSON & JOHNSON INC
EXTRA STRENGTH TYLENOL PAIN AND HEAD COLD NIGHT RAPID RELEASECA	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	MCNEIL CONSUMER HEALTHCARE DIVISION OF JOHNSON & JOHNSON INC
EXTRA STRENGTH TYLENOL NIGHTTIMECA	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	KENVUE CANADA INC.
EXTRA STRENGTH NIGHTTIME PAIN RELIEVER / SLEEP AIDCA	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	TEVA CANADA LIMITED
NEOCITRAN EXTRA STRENGTH COLD & COUGH NIGHTCA	powder Acetaminophen 650 mg + Diphenhydramine 25 mg	HALEON CANADA ULC
NYQUIL HOT REMEDYCA	powder Acetaminophen 650 mg + Diphenhydramine 25 mg	PROCTER & GAMBLE INC
PANADOL NIGHT capsule-shaped tablet blister pack (reformulation)AU	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Haleon Australia Pty Ltd
舒普定膜衣錠TW	tablet Acetaminophen + Diphenhydramine	聯邦化學製藥股份有限公司
U-Comfort F.C. TabletsTW	tablet Acetaminophen + Diphenhydramine	聯邦化學製藥股份有限公司
痛快寧膜衣錠TW	tablet Acetaminophen + Diphenhydramine	寶齡富錦生技股份有限公司
RELAXNIGHT F.C. TABLETS "PBF"TW	tablet Acetaminophen + Diphenhydramine	寶齡富錦生技股份有限公司
PARACETAMOL/DIPHENHYDRAMINE NHPL tablets blister packAU	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Neo Health (OTC) Pty Ltd
CHEMISTS' OWN NIGHT PAIN RELIEF tablet blister packAU	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Arrotex Pharmaceuticals Pty Ltd
PHARMACY CHOICE NIGHT PAIN RELIEF film-coated tablet blister packAU	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	NOUMED PHARMACEUTICALS PTY LTD
COMBOLIEVE DAY & NIGHT PAIN RELIEF tablet blister packAU	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	AFT Pharmaceuticals Pty Ltd
MERSYNONIGHT NIGHT TIME PAIN RELIEF tablet blister packAU	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Opella Healthcare Australia Pty Ltd T/A Opella Healthcare
APOHEALTH NIGHT PAIN RELIEF paracetamol 500 mg/ diphenhydramine hydrochloride 25 mg tablet blister packAU	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Arrotex Pharmaceuticals Pty Ltd
VIDALIFE NIGHT PAIN tablet blister packAU	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Arrotex Pharmaceuticals Pty Ltd
NEOCOMBO DAY & NIGHT PAIN RELIEF tablet blister packAU	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Neo Health (OTC) Pty Ltd
COMBOLIEVE NIGHT PAIN RELIEF paracetamol 500 mg and diphenhydramine hydrochloride 25 mg tablet blister packAU	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	AFT Pharmaceuticals Pty Ltd
BLOOMS THE CHEMIST NIGHT PAIN RELIEF tablet blister packAU	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Arrotex Pharmaceuticals Pty Ltd
TERRYWHITE CHEMMART PARACETAMOL PLUS DIPHENHYDRAMINE tablets blister packAU	tablet Acetaminophen 500 mg + Diphenhydramine 25 mg	Neo Health (OTC) Pty Ltd

Same combination in other markets

No product with this combination is recorded in the other covered markets yet.

Only the main ingredient is the same — this is NOT the same fixed-dose combination. View the main ingredient

See warnings for these ingredients

Source & licence: built from the same regulator data as the ingredient pages (openFDA, dm+d, CIMA, COFEPRIS, PBS/TGA, Health Canada DPD, NHSA). Facts only; see the licence register.